Grisaille (grĭ-zī', -zāl') (from French gris, "grey") is the term for paintings done entirely in monochrome. It is especially used to imitate a relief.

A grisaille could also be used as a first stage in an oil painting, or as a template for an engraver.

Among the churches with grisaille painting in Rome, the best examples are probably those found in Santi Vincenzo e Anastasio.

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